Proceedings of the Komi Science Centre of the Ural Division of the Russian Academy of Sciences Proceedings of the Komi Science Centre of the Ural Division of the Russian Academy of Sciences Известия Коми научного центра УрО РАН 1994-5655 106159 10.19110/1994-5655-2025-7-132-147 Научные статьи Science articles Научные статьи Historical development and cutting-edge applications of enzymes: a review История развития и передовые области применения ферментов (обзор) Мартынов В. В. Martynov V. V. martynov.v.v@ib.komisc.ru Щемелинина Т. Н. Schemelinina T. N. tatyanakomi@mail.ru Анчугова Е. М. Anchugova E. M. Маркарова М. Ю. Markarova M. Yu. Донцов А. Г. Doncov A. G. Институт биологии Коми научного центра Уральского отделения Российской академии наук Сыктывкар Россия Institute of Biology, Komi Science Centre of the Ural Branch of the Russian Academy of Sciences Syktyvkar Russian Federation Институт биологии ФИЦ Коми НЦ УрО РАН Сыктывкар Россия Institute of Biology, Federal Research Center Komi Science Center of the Ural Branch of the Russian Academy of Sciences Syktyvkar Russian Federation Институт биологии ФИЦ Коми НЦ УрО РАН Сыктывкар Россия Institute of Biology, Federal Research Center Komi Science Center of the Ural Branch of the Russian Academy of Sciences Syktyvkar Russian Federation Институт биологии ФИЦ Коми НЦ УрО РАН Сыктывкар Россия Institute of Biology, Federal Research Center Komi Science Center of the Ural Branch of the Russian Academy of Sciences Syktyvkar Russian Federation Институт биологии ФИЦ Коми НЦ УрО РАН Сыктывкар Россия Institute of Biology, Komi Science Centre of the Ural Branch of the Russian Academy of Sciences Syktyvkar Russian Federation 11 11 2025 11 11 2025 7 132 147 05 09 2025 15 09 2025 https://komisc.editorum.ru/en/nauka/article/106159/view

Природные катализаторы – ферменты становятся все более популярными и привлекательными для промышленности благодаря своей экологичности и высокой эффективности по сравнению с традиционными методами. Данный обзор прослеживает путь развития этой области от первых шагов до современных достижений, основанных на тонкой настройке ферментов и их эволюции. Научные статьи обзора были отобраны по ключевым словам, связанным с целлюлолитическими и лигнинолитическими ферментами, штаммами бактерий и грибов, а также использованием промышленных отходов в качестве питательных сред для продуцентов ферментов. Продемонстрированы передовые примеры применения ферментов в промышленности.

The use of enzymes as natural catalysts is gaining a significant industrial traction because of their environmental compatibility and high efficiency compared to the conventional methods. This review outlines the trajectory of this field of research, from its beginnings to its current state, which is characterised by advances in enzyme fine-tuning and directed evolution. Scientific papers for this review have been selected using keywords related to cellulolytic and ligninolytic enzymes, bacterial and fungal strains, and the use of industrial waste as nutrient media for enzyme producers. Cutting-edge examples of enzyme applications in industry are demonstrated.

 ферменты лигноцеллюлозные отходы бактерии грибы питательные среды промышленное производство enzymes lignocellulose waste bacteria fungi nutrient media industrial production Работа выполнена при финансировании государственного задания Института биологии Коми научного центра Уральского отделения РАН по теме «Микробные сообщества экосистем Севера, их биотехнологический потенциал и технологии его реализации» (№ 125021201993-3). The work was funded by the State Assignment of the Institute of Biology of the Komi Scientific Center of the Ural Branch of the Russian Academy of Sciences on the topic «Microbial communities of ecosystems of the North, their biotechnological potential and technologies for its implementation» (№ 125021201993-3).

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